Pentobarbital will decrease the level or effect of aprepitant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. pentobarbital will decrease the level or effect of vincristine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of pantoprazole by affecting hepatic/intestinal e... https://easiestbookmarks.com/story20388601/pentobarbital-vs-phenobarbital-una-panoramica