Within a mouse design, providing genetic validation of CRK12:CYC9 being a novel drug goal for trypanosomiasis. Further, practical characterisation of CRK12 and CYC9 applying RNA interference reveals roles for these proteins in endocytosis and cytokinesis, respectively. CRK12 protein localized towards the plasma membrane, along with the spatiotemporal expression patterns on https://zstk47432198.loginblogin.com/37495185/bms-986141-no-further-a-mystery