Life-threatening respiratory despair and Dying have transpired in little ones who gained codeine. Many of the noted cases occurred subsequent tonsillectomy and/or adenoidectomy and a lot of of the children experienced evidence of getting extremely-immediate metabolizers of codeine because of a cytochrome P450 (CYP) 2D6 polymorphism (see WARNINGS, Safety measures; https://wockusa.com/product/cablivi/